San Francisco 49ers
San Francisco 49ers Monday night in Candlestick Park, the Arizona Cardinals can clinch their second straight NFC West title with a win against the San Francisco 49ers.

When Arizona and San Francisco met in the season opener, the Cardinals' high-powered offense was out of sync and the 49ers' passing game was an afterthought.

NFL odds makers are calling the Cards road favorites coming into this one. The line in Vegas is sitting at, Arizona -4 with the total in the game set at 45.

After a shaky start, Arizona's offense with Warner has looked unstoppable in recent weeks. He has thrown for over 3,000 yards in three straight seasons. His wide receiving tandem of Larry Fitzgerald and Anquan Boldin is the best in the NFL.

The Cards
running game has even looked very good with Beanie Wells and Tim Hightower.

For the 49ers, since quarterback Alex Smith took over the starting roll, he has shined in the new spread offense. He has thrown for 769 yards with seven touchdowns and one interception in his last three games. Only problem is, although they have been putting up the numbers, the have been losing the games.

The Cardinals are have another great year offensively, but it has been their defense that has really improved. After being near the bottom in the conference for years, they are moving up the ladder and play especially well against the run.

Unfortunately, that won't help against the Niners very good passing attack. Look for some serious point to be put up in this one.

Take the over 45 points.