Colts vs Jaguars
Colts vs Jaguars The Colts and the Jacksonville Jaguars face-off at Lucas Oil Stadium in Indianapolis in a big AFC South match-up. The Jags are on the ropes with an 0-2 start while Peyton and the Colts are 1-1. With both teams battered by injured, odds makers are calling the Colts 4 1/2 point favorites at home with the total sitting at 41 1/2.

The Colts rallied late to beat the Vikings a week ago to avoid an 0-2 start, but they still suffered a huge lose. Pro Bowl safety Bob Sanders' sprained ankle against Minnesota will keep him out of the lineup Sunday and could keep him side-lined for up to six weeks. Even with Sanders in the lineup the Colts have struggled stopping the run.

"With a guy like Bob, of course, there's going to
be some drop off," said Colts defensive end Dwight Freeney. "Maybe you won't see someone make that spectacular play, but you've still got to make plays. When one guy goes down, another guy has to step up, and there have to be 11 guys swarming to the ball."

So far the Jaguars are near the bottom of the league in rushing in 2008. Jacksonville's struggles stem from a beat up offensive line. Maurice Jones-Drew and 11-year veteran Fred Taylor have not been able to get anything going on the ground thus far.

"Must win, it's the stupidest phrase ever invented," Taylor said. "Why would you want to lose at anything?"

The Colts expect to have center Jeff Saturday and tight end Dallas Clark back this week against the Jags. Take Indianapolis at home and give the 4 1/2.